{"id":33735,"date":"2025-08-19T19:34:56","date_gmt":"2025-08-19T16:34:56","guid":{"rendered":"https:\/\/kibrisayna.com\/index.php\/2025\/08\/19\/bilim-insanlari-simdiye-kadarki-en-sentetik-canliyi-olusturdu-son-dakika-teknoloji-haberleri\/"},"modified":"2025-08-19T19:34:56","modified_gmt":"2025-08-19T16:34:56","slug":"bilim-insanlari-simdiye-kadarki-en-sentetik-canliyi-olusturdu-son-dakika-teknoloji-haberleri","status":"publish","type":"post","link":"https:\/\/kibrisayna.com\/index.php\/2025\/08\/19\/bilim-insanlari-simdiye-kadarki-en-sentetik-canliyi-olusturdu-son-dakika-teknoloji-haberleri\/","title":{"rendered":"Bilim insanlar\u0131 \u015fimdiye kadarki en sentetik canl\u0131y\u0131 olu\u015fturdu – Son Dakika Teknoloji Haberleri"},"content":{"rendered":"


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Bilim<\/a> insanlar\u0131, d\u00fcnyadaki herhangi bir canl\u0131dan \u00e7ok daha sadele\u015ftirilmi\u015f ve de\u011fi\u015ftirilmi\u015f genetik koda sahip yeni bir bakteri<\/a> \u00fcretti.<\/p>\n

Syn57 ad\u0131 verilen sentetik \u201cEscherichia coli\u201d bakterisi t\u00fcr\u00fc, ya\u015fam\u0131n temel dilini olu\u015fturan 64 kodondan yaln\u0131zca 57\u2019sini kullanarak v\u00fccudunu in\u015fa edecek \u015fekilde tasarland\u0131. Bu, bug\u00fcne kadar elde edilen en \u201ck\u00fc\u00e7\u00fclt\u00fclm\u00fc\u015f\u201d genetik planlama olarak kayda ge\u00e7ti.<\/p>\n

Kodon, DNA veya RNA\u2019daki 3 n\u00fckleotidlik (\u00fc\u00e7 harflik) birimlere verilen isim. DNA ve RNA\u2019n\u0131n alfabesi 4 harften (n\u00fckleotid) olu\u015fuyor: A, T, G, C. Bu harfler \u00fc\u00e7l\u00fc gruplar halinde dizilir. Her \u00fc\u00e7l\u00fc, yani kodon, bir anlam ta\u015f\u0131yor.<\/p>\n

Ya\u015fam\u0131n tarifi, \u00fc\u00e7 n\u00fckleotidden olu\u015fan 64 farkl\u0131 kodona dayan\u0131yor. H\u00fccreler, bu \u00fc\u00e7 harfli kodonlar\u0131 okuyarak hangi amino asidin \u00fcretilece\u011fini ve protein zincirine hangi s\u0131rayla eklenece\u011fini belirliyor.<\/p>\n

Ancak do\u011fadaki sistemde gereksiz tekrarlar bulunuyor; canl\u0131lar 20 amino asit ile hayatta kalabiliyor, dolay\u0131s\u0131yla bir\u00e7ok kodon ayn\u0131 i\u015flevi ta\u015f\u0131yor.<\/p>\n

SIFIRDAN TASARLANDI<\/strong><\/p>\n

\u0130ngiltere\u2019deki Medical Research Council Molecular Biology Laboratuvar\u0131 ara\u015ft\u0131rmac\u0131lar\u0131, bu tekrarlar\u0131 ortadan kald\u0131rmak i\u00e7in bakterinin t\u00fcm genomunu s\u0131f\u0131rdan tasarlad\u0131. Baz\u0131 i\u015flemler i\u00e7in genetik kodda 101 binden fazla de\u011fi\u015fiklik yap\u0131ld\u0131.<\/p>\n

Genetik<\/a> par\u00e7alar bilgisayarda tasarland\u0131ktan sonra k\u00fc\u00e7\u00fck b\u00f6l\u00fcmler halinde bakterilere aktar\u0131ld\u0131 ve test edildi. Ard\u0131ndan bu par\u00e7alar birle\u015ftirilerek tamamen sentetik ve \u00e7al\u0131\u015f\u0131r halde bir bakteri elde edildi.<\/p>\n

\u00c7al\u0131\u015fman\u0131n ba\u015fyazarlar\u0131ndan sentetik biyolog Wesley Robertson, s\u00fcrecin zorluklar\u0131na dikkat \u00e7ekerek, \u201cBazen ger\u00e7ekten \u00e7\u0131kmaz yolda m\u0131y\u0131z, yoksa bunu tamamlayabilir miyiz diye d\u00fc\u015f\u00fcnd\u00fck\u201d dedi.<\/p>\n

YEN\u0130 UFUKLAR<\/strong><\/p>\n

Syn57, genetik kodun ciddi \u00f6l\u00e7\u00fcde s\u0131k\u0131\u015ft\u0131r\u0131lm\u0131\u015f haliyle ya\u015fam\u0131n s\u00fcrd\u00fcr\u00fclebilece\u011fini g\u00f6steriyor. Ayr\u0131ca bo\u015fta kalan kodonlar, farkl\u0131 roller \u00fcstlenmek \u00fczere yeniden tan\u0131mlanabilir. Ara\u015ft\u0131rmac\u0131lar, bunun yeni sentetik polimerler ve makrosikller geli\u015ftirme imkan\u0131 sundu\u011funu belirtiyor.<\/p>\n

Bir di\u011fer \u00f6nemli nokta ise, Syn57\u2019nin s\u0131ra d\u0131\u015f\u0131 genetik kodunun vir\u00fcsler taraf\u0131ndan okunamamas\u0131. Bu \u00f6zellik, bakterilerin end\u00fcstriyel \u00f6l\u00e7ekte protein \u00fcretiminde vir\u00fcs kaynakl\u0131 kay\u0131plar\u0131 azaltabilir.<\/p>\n

Ayr\u0131ca genetik olarak de\u011fi\u015ftirilmi\u015f bu bakterilerin do\u011fal \u00e7evreye kar\u0131\u015fmas\u0131 durumunda \u00fcreyememesi, biyog\u00fcvenlik a\u00e7\u0131s\u0131ndan avantaj sa\u011flayabilir.<\/p>\n

\u00c7al\u0131\u015fman\u0131n sonu\u00e7lar\u0131 Science dergisinde yay\u0131mland\u0131.<\/p>\n<\/div>\n


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<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Bilim insanlar\u0131, d\u00fcnyadaki herhangi bir canl\u0131dan \u00e7ok daha sadele\u015ftirilmi\u015f ve de\u011fi\u015ftirilmi\u015f genetik koda sahip yeni bir bakteri \u00fcretti. Syn57 ad\u0131 verilen sentetik \u201cEscherichia coli\u201d bakterisi t\u00fcr\u00fc, ya\u015fam\u0131n temel dilini olu\u015fturan 64 kodondan yaln\u0131zca 57\u2019sini kullanarak v\u00fccudunu in\u015fa edecek \u015fekilde tasarland\u0131. Bu, bug\u00fcne kadar elde edilen en \u201ck\u00fc\u00e7\u00fclt\u00fclm\u00fc\u015f\u201d genetik planlama olarak kayda ge\u00e7ti. Kodon, DNA veya […]<\/p>\n","protected":false},"author":908,"featured_media":33736,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[12],"tags":[],"class_list":["post-33735","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-teknoloji"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/kibrisayna.com\/wp-content\/uploads\/2025\/08\/tDS3IQzKGUug8j7einZVEA.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/kibrisayna.com\/index.php\/wp-json\/wp\/v2\/posts\/33735","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kibrisayna.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kibrisayna.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kibrisayna.com\/index.php\/wp-json\/wp\/v2\/users\/908"}],"replies":[{"embeddable":true,"href":"https:\/\/kibrisayna.com\/index.php\/wp-json\/wp\/v2\/comments?post=33735"}],"version-history":[{"count":0,"href":"https:\/\/kibrisayna.com\/index.php\/wp-json\/wp\/v2\/posts\/33735\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kibrisayna.com\/index.php\/wp-json\/wp\/v2\/media\/33736"}],"wp:attachment":[{"href":"https:\/\/kibrisayna.com\/index.php\/wp-json\/wp\/v2\/media?parent=33735"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kibrisayna.com\/index.php\/wp-json\/wp\/v2\/categories?post=33735"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kibrisayna.com\/index.php\/wp-json\/wp\/v2\/tags?post=33735"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}